You can take a prenatal multivitamin at any time of day. But it’s ideal to take your multivitamin together with a meal because it not only helps the tablet to disintegrate, it also makes it easier for your body to absorb the vitamin’s nutrients. Taking a prenatal multivitamin at mealtime helps minimize the potential for stomach upset, as well (especially if you are sensitive to iron). You’ll also find it easier to incorporate your prenatal multivitamin into your daily routine if you take it at the same time every day.